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Courtyard Cape Girardeau Downtown epitomizes historic charm, once serving as a bank in the early 1900s before its transformation into a boutique-style hotel. Nestled in the heart of downtown, it provides easy access to an array of distinctive bars and restaurants, along with the Southeast Missouri State University campus. Our on-site bistro caters to guests with delectable breakfast and dinner choices, complemented by a full bar featuring an impressive bourbon selection and more, perfect for evening unwinding.

Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown and within walking distance to many shops and restaurants. Settle in for a relaxing stay in one of our modern guest rooms. Enjoy the convenience of a mini-refrigerator, microwave, free WiFi, coffeemaker, 42-inch flat-screen TV with premium cable channels and work desk with ergonomic chair. Upgrade to a studio suite for extra space and a separate seating area. Start each day with our free hot breakfast or, if you’re in a hurry, grab one of Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stop by our Treats Shop any time of day or night for a quick snack or beverage. Stay in shape with a workout in our 24-hour fitness center or take a dip in our indoor heated pool. Plan a meeting in our 700 sq. ft. of meeting space fully equipped with A/V equipment.

incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.

Welcome to the New Holiday Inn Express & Suites Union City, Union City’s newest and most modern Holiday Inn Express hotel that is nestled within the growing development in Houser Creek Crossing next to Discovery Park of America. The hotel is located off of Highway 51. The hotel features 15 spacious suites and 4 kid suites and all the rooms include a microwave, refrigerator, large flat panel television, Keurig Brewer, along with fast and complimentary high-speed Internet throughout the hotel. The hotel features a free Express Start™ Breakfast Bar, indoor heated pool, guest laundry and 24/7 Business Center. Travelers can benefit from the proximity of our Holiday Inn Express & Suites Union where guests will be close to many nearby companies including Tyson Foods, Williams Sausage Company, Baptist Memorial Hospital, Titan Tire, Kohler, MVP Brands, Greenfield Products, Institutional Caseworks, Waymatic and MIA Seating. Our non-smoking Holiday Inn Express & Suites Union City offers easy access to several attractions including Discovery Park of America, Reelfoot Lake, White Squirrel Winery, Full Throttle Distillery and Dixie Gun Works Museum.Don’t hesitate to book your stay for your next leisure or business trip at the Holiday Inn Express & Suites Union City. When using GPS put in Discovery Park America it will bring you right next door to us.

When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System. Be sure to enjoy recreational amenities, including an indoor pool, a spa tub, and a fitness center. Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served daily. Featured amenities include a 24-hour business center, a 24-hour front desk, and laundry facilities. Event facilities at this hotel consist of a conference center and meeting rooms. Free self parking is available onsite. Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.

Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!

With a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Steele Crest Winery and Lazy L Safari Park. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest. Take advantage of recreational opportunities offered, including an indoor pool, a spa tub, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access and a television in a common area. Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served daily. Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.

With a stay at Auburn Place Hotel And Suites in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.9 mi (1.5 km) from Saint Francis Medical Center and 2.4 mi (3.8 km) from Saint Francis Healthcare System. Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, barbecue grills, and a vending machine. Grab a bite from the grocery/convenience store serving guests of Auburn Place Hotel And Suites. A complimentary buffet breakfast is served daily. Featured amenities include complimentary wired internet access, a 24-hour business center, and dry cleaning/laundry services. Make yourself at home in one of the 133 air-conditioned rooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, and housekeeping is provided daily.

With a stay at EC Reed's Mercantile and Hotel in Marble Hill, you'll be 12.7 mi (20.4 km) from Bollinger Mill State Historic Site and 29.9 mi (48.1 km) from Southeast Missouri State University. This hotel is 31.2 mi (50.2 km) from Isle Casino Cape Girardeau. This smoke-free hotel features hiking/biking trails nearby, kayaking nearby, and rafting nearby. Recreational activities include canoeing nearby. You can enjoy a meal at Soda and Ice Cream Shop serving the guests of EC Reed's Mercantile and Hotel, or stop in at the snack bar/deli. Mingle with other guests at the complimentary reception, held daily. A complimentary continental breakfast is served daily from 6:30 AM to 9:30 AM. Featured amenities include express check-in and coffee/tea in a common area. Free self parking is available onsite. Make yourself at home in one of the 14 air-conditioned rooms featuring Smart televisions. Complimentary wireless internet access keeps you connected, and digital programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include complimentary bottled water, as well as phones with free local calls.

Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis Healthcare System. This hotel is 4.6 mi (7.5 km) from Shawnee National Forest and 5 mi (8.1 km) from Mississippi River. Take advantage of recreation opportunities such as a fitness center, or other amenities including complimentary wireless internet access and a television in a common area. A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM. Featured amenities include a 24-hour business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite. Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.